European stocks appeared set to open lower on Wednesday, as investors remained wary amid uncertainty surrounding U.S. President Donald Trump's shifting trade strategies. During the early premarket session, futures for the Euro Stoxx 50 and Stoxx 600 dropped by 1.2% and 1%, respectively, suggesting a widespread downturn across the region. Market participants are also keeping a close eye on significant economic reports, such as the UK's inflation figures and the Eurozone's current account data, for further guidance. On the corporate side, investor confidence was shaken by ASML's latest earnings announcement. The Dutch semiconductor company's report revealed first-quarter net bookings that fell short of expectations, sparking concerns about a potential decline in chip demand.