European equity markets appeared poised for a lower opening on Wednesday, as investors considered escalating geopolitical tensions in the Middle East alongside anticipation of the US Federal Reserve's forthcoming interest rate decision. Market sentiment deteriorated following comments from US President Donald Trump, who insisted on Iran’s "unconditional surrender" and threatened action against Supreme Leader Khamenei, further inflaming Middle Eastern tensions. In Europe, focus will also be on the release of new UK inflation data and a monetary policy decision from Sweden’s Riksbank, both of which could impact regional interest rate expectations. During premarket trading, futures for the Euro Stoxx 50 declined by 0.3%, while those for the Stoxx 600 fell by 0.2%.